What is an endometrial pipelle biopsy?

This is the name of the procedure which takes a small sample of tissue from the lining of the womb (endometrium). This sample is then sent off to the laboratory to check if you have any cancer or other abnormal cells in the lining of your womb.

The biopsy may give answers to:

  • Why you are having abnormal vaginal bleeding (heavy or prolonged periods, or bleeding between periods.
  • Why you are having some bleeding after the menopause.
  • Why an ultrasound scan shows you have a thickened lining of your womb.

Who is the biopsy not suitable for?

The biopsy is not suitable for you if you:

  • Are pregnant
  • Have an infection in the vagina or pelvis
  • Have pelvic inflammatory disease

What is the benefit?

The benefit of having the biopsy taken is to check for any abnormal cells or signs of cancer so that treatment can be offered for your condition.

What are the risks?

The procedure is generally very safe. You may experience mild period type pain during the procedure. 

In rare cases, patients may be at risk of:

  • Prolonged bleeding
  • Infection
  • Uterine perforation (making a hole in the womb) but this is very rare.

Sometimes it can be difficult to get the biopsy, especially if you haven’t had any children or have had treatment in the past to your cervix – in this case we may have to consider referring you to hospital to see a gynaecologist.

Preparing for the biopsy

You don’t need to do anything in preparation for your biopsy. You are still able to have the procedure carried out if you are in your period or experiencing some postmenopausal bleeding.

Pipelle Biopsy:

The doctor and nurse will explain and take your written consent prior to procedure.

The chaperone nurse will be with you throughout the examination and procedure.

The biopsy is done by passing a thin plastic straw through the cervix into the womb. The biopsy is taken by slight suction as the inside of the straw is pulled out causing the suction. This part of the procedure can cause the crampy period type pain that is often experienced. This pain generally, settles once the procedure is finished, but a few women may feel like they want some simple painkillers.

After the biopsy

If you experience any tummy discomfort for which you can take some Paracetamol or Ibuprofen that you may have at home. You are able to go to work if you are feeling well and are also able to drive after the procedure.

You may experience some vaginal bleeding for the next day or so after having the biopsy taken and this is completely normal. It is advisable to wear a sanitary pad just in case this happens. You can continue with normal activities such as having a bath or shower, exercise and driving. We recommend that you do not have sex until the bleeding has stopped completely.

It can take between 1 – 2 weeks before you receive the letter with the results. We will call you about the results or you can come in to discuss the results. If you require further treatment, a specialist referral will be organised.

Symptoms to report

If you start experiencing heavy bleeding, or strong-smelling discharge, then we advise you to contact us as you may have an infection and need some medication.